What is the greatest clinical danger of acute DVT?

The greatest clinical danger of acute Deep Vein Thrombosis (DVT) is the risk of pulmonary embolism. When a DVT forms, there is a potential for the thrombus (blood clot) to dislodge and travel through the venous system to the lungs. If the clot reaches the pulmonary arteries, it can obstruct blood flow, leading to a pulmonary embolism, which can result in serious complications such as decreased oxygenation, respiratory distress, or even death.

While local pain and swelling are significant symptoms of DVT and superficial vein complications can occur, these are not life-threatening conditions. Skin ulceration, while a concern for chronic venous insufficiency, is not an immediate hazard associated with acute DVT. Thus, the possibility of a pulmonary embolism represents the most severe and urgent consequence of an acute DVT situation, emphasizing the importance of early diagnosis and treatment to mitigate this risk.